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A group of scientists discovered Stromectol's potential to counter parasitic infections in 1975. By the 1980s, it became a popular veterinary antiparasitic in many countries. Its effectiveness in treating parasitic infections in cattle and other animals prompted a group of Merk scientists and the World Health Organization to test the drug's effectiveness in humans.
It took a few years of research and a series of trials for the FDA to approve its use in humans. The drug effectively cleared onchocerciasis infections in humans. Additionally, scientists uncovered that it was safe for human consumption. Therefore, the FDA approved its use to treat and prevent parasitic infestations. The approval saw the rise of Ivermectin campaigns to eradicate river blindness and lymphatic filariasis. The campaigns targeted endemic areas.
The campaigns have reduced lymphatic filariasis, river blindness, and other parasitic infestation incidences globally.
Action in the Body
Stromectol binds to glutamate-controlled chloride ion channels (GluCl) found on the parasites' nerves and muscle cells. The GluCl pathways control the membrane permeability. Therefore, Stramectol's attachment to GluCl channels increases the parasites' cell membrane permeability to chloride ions. The increased permeability leads to hyperpolarization, which causes paralysis and death of these parasites. Therefore, the medication will prevent parasites from moving, eating, or multiplying.
Uses
Stromectol is highly effective against a variety of parasites, including nematodes like
Therefore, the medication can treat the following.
It's also known as onchocerciasis. A parasitic worm transmitted to humans through an infected blackfly's bite causes it. The worms can live in the body for up to 15 years. The infection causes skin rash, itching, and blindness.
It's a parasitic infection that causes skin rash, abdominal pain, and diarrhea. It can also lead to complications in people with compromised immune systems.
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Physicians also use it to treat tropical infections like filariasis, loa loa infection, et cetera. It can also treat head lice, scabies, and other skin conditions caused by mites.
Medication and Duration of Dosage
The medication comes as an oral tablet. Your doctor will prescribe it as a series of or a single dose, depending on the parasitic condition you're treating.
Note: Always ingest the medication orally. Take it with a whole glass of water one hour before a meal. You'll need to take it on an empty stomach.
The dosage level often depends on one's weight and medical condition. The patient's response to treatment may also come into play. The duration of the Stromectol treatment plan will also vary depending on the severity of the parasitic infection.
Also, get a medical opinion before taking Stromectol. You'll need to adhere to your doctor's instructions for the medication to work.
Warning: Do not stop treatment early: It is crucial to complete your dose, even if symptoms improve before the end of treatment. Stopping the treatment before completing the prescribed treatment course puts you at risk of recurrence of the parasitic infection.
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Side Effects
While Stromectol is generally well-tolerated, it causes the following side effects.
Common Side Effects
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Nausea
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Vomiting
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Diarrhea
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Dizziness
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Headache
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Fatigue
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Abdominal pain
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Loss of appetite
In rare cases, Stromectol may cause serious side effects, such as:
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Seizures
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Confusion
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Depression
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Loss of consciousness
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Allergic reactions
Note that this is not an exhaustive list of the possible Stromectol side effects. You may experience other side effects. You'll need to see your physician if you develop any unusual side effects while taking Stromectol,
Precautions
Most people tolerate Stromectol without developing any complications. But you'll need to consider certain precautions before taking it.
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Allergies- Consult your provider if you're allergic to ivermectin and other Stromectol ingredients before taking the drug. Also, inform your doctor of any history of allergies or adverse reactions to other medications.
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Drug interactions- Stromectol presents adverse interactions with certain medications, such as blood thinners, seizure drugs, and antibiotics.
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Pregnancy and breastfeeding- Use Stromectol with caution if you're pregnant or breastfeeding women.
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Driving and operating machinery- The medication may cause dizziness and other side effects that may impair a person's ability to drive or operate machinery. Don't operate or drive machinery while using the medication.
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Alcohol consumption- Avoid Alcohol while taking Stromectol. Alcohol heightens the risk of severe side effects.
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Bottom Line
Stromectol is a potent medication prescribed to treat parasitic infections. It has exhibited unparalleled efficacy in combating river blindness and strongyloidiasis.
Most people tolerate it without developing severe side effects or complications. However, it's not unusual to experience unwanted side effects. Therefore, always take the medication under a doctor's supervision. You'll also need to comply with your physician's recommendations.
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